Jaringan Laboratorium Medis

Vol. 2 No. 1 (2020): May 2020
Original Articles

Overview of Ureum and Creatinine Levels in Hemodialysis Patients with Chronic Kidney Disease

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  • Roni Afriansya,
  • Eko Naning Sofyanita,
  • Suwarsi
Roni Afriansya
Poltekkes Kemenkes Semarang
Eko Naning Sofyanita
Poltekkes Kemenkes Semarang
Suwarsi
Poltekkes Kemenkes Semarang

Published 2023-11-30

Keywords

  • Chronic Kidney Disease,
  • Hemodialysis,
  • Ureum and Creatinine Levels

Copyright (c) 2020 Jaringan Laboratorium Medis

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This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

How to Cite

Overview of Ureum and Creatinine Levels in Hemodialysis Patients with Chronic Kidney Disease. (2023). Jaringan Laboratorium Medis, 2(1), 6-11. https://doi.org/10.31983/jlm.v2i1.5813

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Abstract

Chronic Kidney Disease is evident if the blood urea level is more than 200 mg/dl. Uremia causes a malfunction in almost all organ systems such as; fluid and electrolyte disorders, metabolic endocrine, neuromuscular, cardiovascular and pulmonary, skin, gastrointestinal, hematological, and immunological. Hemodialysis is an attempt to reduce the symptoms of uremia so that the patient's clinical condition can also improve. The purpose of this study was to determine the description of Ureum and Creatinine in CKD Patients undergoing Hemodialysis. This type of research is observational descriptive. The sample included all CKD patients undergoing hemodialysis in 2019 who met the inclusion criteria, so as many as 83 samples were obtained. The type of data is secondary data obtained from medical records. The results showed that most patients were in the 40-60 years age group of 72% and the majority of the male sex were 51 patients (61%). Urea and creatinine appearance in patients undergoing hemodialysis has increased very high. In 83 patients with CKD increased serum creatinine levels (> 100%) with a mean creatinine level in men of 11.80 mg / dL and women of 9.73 mg / dL and an increase in ureum levels with a mean of 167 men, 09 mg / dL and women of 164.39 mg / dL. This study concludes that all patients with CKD have increased levels of urea and creatinine by more than 100%.

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References

  1. Alfonso, A. A., Mongan, A. E., dan Memah, M. F. (2016). Gambaran kadar kreatinin serum pada pasien penyakit ginjal kronik stadium 5 non dialisis. eBiomedik, 4(1).
  2. Banerjee A. (2005). Renal physiology. In : Clinical physiology an examination primer. USA : Cambridge University Press;.p.61.
  3. Guyton AC, Hall JE. Pembentukan urin oleh ginjal: 1. Filtrasi glomerulus, aliran darah ginjal, dan pengaturannya. Dalam: Buku ajar fisiologi kedokteran. Edisi 9. Jakarta: EGC; 1997.p.397-8.
  4. Martini, M. (2010). Hubungan Tingkat Asupan Protein Dengan Kadar Ureum Dan Kreatinin Darah Pada Penderita Gagal Ginjal Kronik Di Rsud Dr. Moewardi Surakarta (Doctoral dissertation, Universitas Muhammadiyah Surakarta).
  5. National Kidney Foundation - Kidney Disease Improving Global Outcomes (NKF-KDIGO). KDIGO. (2012). clinical practice guideline for the evaluation and management of chronic kidney disease. ISN. 2013;3(1):1-163.
  6. National Institute for Helath Research. (2014). Point-of-care creatinine testing for the detection and monitoing of chronic kidney disease. Oxford Journal.1-3.
  7. Hill, N. R., Fatoba, S. T., Oke, J. L., Hirst, J. A., O’Callaghan, C. A., Lasserson, D. S., and Hobbs, F. R. (2016). Global prevalence of chronic kidney disease–a systematic review and meta-analysis. PloS one, 11(7).
  8. Pura, L., Supriyadi, R., Nugraha, G. I., Bandiara, R., dan Soelaeman, R. (2009). Hubungan laju filtrasi glomerulus dengan status nutrisi pada penderita penyakit ginjal kronik predialisis. Majalah Kedokteran Bandung, 41(1).
  9. Suwitra, K. (2014). Penyakit Gagal Ginjal Kronik. Buku Ajar Ilmu Penyakit Dalam. Edisi ke-5. Jakarta: Internal publishing.
  10. Sukandar, E. (2006). Nefrologi klinik. Edisi ketiga. Bandung: Pusat Informasi Ilmiah (PII) Bagian Ilmu Penyakit Dalam Fakultas Kedokteran UNPAD.
  11. Skorecki, K., and Bargman, J. M. (2012). Chronic Kidney Disease. Harrison's Principals of Internal Medicine. Newyork: McGraw-Hill Inc, 18(2), 2308.
  12. Tjekyan R. (2014). Prevalensi dan Faktor Risiko penyakit ginjal kronik di RSUP Dr. Mohammad Hoesin Palembang Tahun 2012. Jurnal Fakultas Kedokteran Universitas Sriwijaya. 277.
  13. Wahyuni, P., Miro, S., dan Kurniawan, E. (2018). Hubungan Lama Menjalani Hemodialisis dengan Kualitas Hidup Pasien Penyakit Ginjal Kronik dengan Diabetes Melitus di RSUP Dr. M Djamil Padang. Jurnal Kesehatan Andalas, 7(4), 480-485.
  14. Wilson, LM. (2005). Penyakit ginjal kronik stadium akhir: sindrom uremik. In: Pendit BU, Hartanto H, Wulansari P, Mahanani DA, Susi N (editor Bahasa Indonesia). Patofisiologi konsep klinis proses-proses penyakit Vol-2 (6th ed). Jakarta: EGC, 45.p. 951-62.
  15. De Nicola, L., et al. (2012). The effect of increasing age on the prognosis of non-dialysis patients with chronic kidney disease receiving stable nephrology care. Kidney international, 82(4), 482-488.