Jaringan Laboratorium Medis

Vol. 2 No. 2 (2020): November 2020
Original Articles

Profile of SGPT Levels in Multidrug Resistant Tuberculosis Patients (MDR-TB)

PDF
  • Meisika Damayanti,
  • Surati
Meisika Damayanti
Poltekkes Kemenkes Semarang
Surati
Poltekkes Kemenkes Semarang

Published 2023-12-01

Keywords

  • MDR-TB,
  • SGPT levels

Copyright (c) 2020 Jaringan Laboratorium Medis

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

How to Cite

Profile of SGPT Levels in Multidrug Resistant Tuberculosis Patients (MDR-TB). (2023). Jaringan Laboratorium Medis, 2(2), 68-74. https://doi.org/10.31983/jlm.v2i2.7687

CrossMark



Dimensions

If it doesn't Appear, click here



PlumX Metrics



Impact Factor

or, Visit on here

Abstract

Multidrug Resistant Tuberculosis (MDR-TB) has recently become a health threat in Indonesia. The clinical management of MDR TB is more complicated than that of ordinary TB. Hepatotoxicity or commonly known as Anti-Tuberculosis Drug-induced Hepatotoxicity (ATDH) is a serious effect of OAT that often occurs. The basic parameter for diagnosing or following up the presence of impaired liver function is the SGPT examination. The purpose of this study was to describe the level of SGPT in MDR-TB patients. This study is an observational (non-experimental) study with descriptive research criteria with a cross sectional approach which was conducted on 7 MDR-TB patients at Kendal I Health Center, Kaliwungu Health Center, and South Kaliwungu Health Center with total sampling technique. The results of the study: obtained SGPT levels in 7 patients with MDR-TB there were 7 research respondents (100%) had normal SGPT levels with the lowest level of 2.17 U/L and the highest level of 37.75 U/L and the average level of SGPT ie 18.01 U/L. TB mostly attacks the age group of 56-65 years (57%). Males (57%) were the patients with the most TB cases. The most OAT consumption time was in the continuation phase (100%). Diabetes is a disease that often accompanies TB patients. The conclusion of this study is that from 7 research subjects, MDR-TB patients had SGPT levels that were in the normal range.

PDF

Downloads

Download data is not yet available.

References

  1. Chairini, S., & Widodo, W. (2020). Profile of SGOT and SGPT levels in Patients with Pulmonary Tuberculosis. Jaringan Laboratorium Medis, 2(1), 18-21.
  2. Kalma. (2016). Studi Hasil Pemeriksaan Serum Glutamic Oxalacetic Transaminase Dan Serum Glutamic Phyruvic Transaminase Pada Penderita Tuberkulosis Paru Sebelum Dan Setelah Satu Bulan Mengkonsumsi Obat Anti Tuberkulosis. VII(2), 7–18.
  3. Nurrizqi, T. M. (2017). Pemeriksaan Kadar SGOT dan SGPT pada Penderita Tuberkulosis Akhir Fase Intensif 60.
  4. Raharjo, W., Lestari, R. H., dan Uwan, W. B. (2019). Gambaran Kadar Enzim Transaminase Pada Pasien Tuberkulosis Yang Mendapat Terapi Obat Anti Tuberkulosis Di Unit Pengobatan Penyakit Paru-Paru Provinsi Kalimantan Barat. Jurnal Mahasiswa PSPD FK Universitas Tanjungpura, Vol 5, No, 2–11.
  5. Rasyid, S. A., Armayani, Yuniati, and Lio, T. M. P. (2020). Analysis of Serum Glutamic Pyruvic Transaminase and Serum Glutamic Oxaloacetic Transaminase Levels in Tuberculosis Patient Who are Undergoing Oat Treatment in Kendari City General Hospital, Kota Kendari Indonesia. 12, 75–77. https://doi.org/10.4081/idr.2020
  6. Rizky, V., Wulan, W. S., Kesehatan, J. A., dan Surabaya, P. K. (2019). Vol 8 No . 2 Desember 2019 Issn : 2320 - 3635 Issn : 2320 - 3635. Pengaruh Waktu Penanganan Pemeriksaan Terhadap Kadar Sgpt Pada Serum dan Plasma Edta, 8(2), 777–781.
  7. Saputri, I. N., dan Munthe, E. L. (2020). Tuberkulosis Resisten Ganda (TB-MDR) dan Implementasi Upaya Pengendalian di Kabupaten Ketapang. Jurnal Respirologi Indonesia, 40(1).
  8. Sri, Rahayu & Sukeksi, A. (2017). Hubungan Kadar SGOT-SGPT Pada Pasien TB Pengobatan Fase Awal Di Puskesmas Pati. Repository Unimus.
  9. Sumiati, D., & Budiharjo, T. (2019). BTA Suspect Findings Before and After Knocking on the Doors Program by Cadre Based on Quality of Sputum Samples. Jaringan Laboratorium Medis, 1(1), 34-37.
  10. WHO. (2019). WHO TB Report. WHO Library Cataloguing-in-Publication Data World, 7.
  11. Winadiatri, H. (n.d.). Metabolisme Obat Pada Penyakit Kardiovaskuler Halia Winadiatri. 20, 1–4.