Jaringan Laboratorium Medis

Vol. 2 No. 2 (2020): November 2020
Original Articles

Literature Study Overview of C-Reactive Protein in Hypertensive Patients

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  • Umi Fadilah,
  • Djoko Priyatno
Umi Fadilah
Rumah Sakit Omni Pulomas

Published 2023-12-01

Copyright (c) 2020 Jaringan Laboratorium Medis

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How to Cite

Literature Study Overview of C-Reactive Protein in Hypertensive Patients. (2023). Jaringan Laboratorium Medis, 2(2), 82-88. https://doi.org/10.31983/jlm.v2i2.7696

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Abstract

Hypertension is called the silent killer, often known after complications occur. Based on the results of Riskesdas in 2018, the prevalence of hypertension in Indonesia at age ≥18 years increased to 34.1% in 2018. Endothelial injury caused by hypertension triggers inflammation or chronic inflammation of the arterial wall. Evidence of an inflammatory process is the discovery of C-Reactive Protein (CRP) which is a marker of inflammation from non-bacterial infections.The purpose of this study to knowing the description of C-Reactive Protein in patients with hypertension through research by Fadhliani (2016), Dolly (2018), Harahap (2019). This paper is a summary of  research result, with the criteria for systematic study research through a systematic review approach. In patients with hypertension according to research Fadhliani (2016) obtained as much as 23% C-Reactive Protein positive and 77% C-Reactive Protein negative. In the Harahap study (2019) of 30 people with hypertension, 12 people (40%) had positive C-Reactive Protein and 18 people (60%) had negative C-Reactive Protein. Whereas in the study of Dolly (2018) the average level of hs-CRP in hypertensive patients is 4, 85 mg / L. According to Dolly's research (2018) in patients with hypertension for > 1 year have higher levels of hs-CRP compared to patients with hypertension for a period of ≤1 years. Examination of C-Reactive Protein (CRP) in patients with hypertension in the Harahap study (2019) showed positive CRP results dominated by subjects with age ≥ 50 years as many as 8 people (27%).

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